Assoc. Prof. Dr. Yingying Wu | Genetic Research | Research Excellence Award
Research Director | Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences | China
Assoc. Prof. Dr. Yingying Wu is a dedicated researcher whose work focuses on the genetic breeding of industrialized edible mushrooms and the synthetic biology of active natural products from macrofungi, contributing significantly to biotechnology, functional food development, and mushroom-based pharmaceutical innovation. Her research explores the improvement of mushroom strains to enhance production efficiency, nutritional composition, and bioactive properties valuable for human health. She has contributed to metabolic profiling studies of Cordyceps militaris, identifying optimal consumption periods to maximize functional health effects and sensory qu`ality, providing scientific foundations for promoting mushroom products as high-value nutraceuticals. Her work on the cloning, characterization, and functional analysis of novel fungal immunomodulatory protein genes, such as those found in Ganoderma leucocontextum, demonstrates the therapeutic potential of macrofungi-derived biomolecules in immune regulation and cancer-related cellular functions. Additionally, she has advanced understanding of reproductive biology and nuclear behavior in edible mushroom strains through studies on protoplast monokaryotization and asexual spore isolation in Flammulina filiformis, supporting efficient breeding technologies for industrial cultivation. By integrating molecular biology, metabolic analysis, and applied breeding strategies, she contributes to creating sustainable and innovative mushroom-derived products, strengthening the link between food technology and biomedical research. Her scientific outputs reflect meaningful contributions to both fundamental mycological research and practical industrial applications, positioning her as a promising leader in the field of macrofungi biotechnology, functional active compound discovery, and future health-focused bioindustries.
Featured Publications
Wang, Y., Zhang, R., Li, Y., Wu, Y., Gong, M., Shao, Y., Wang, L., Li, W., & Zou, G. (2026). Metabolic profiles reveal the preferable consumption time of Cordyceps militaris dried products with the optimal health effects and flavors. Journal of Future Foods, 6(4), 642–655.
Yang, J., Jin, M., Zhang, L., Wu, Y., & Zhou, X. (2025). Characterization and functional analysis of a novel fungal immunomodulatory protein gene from Ganoderma leucocontextum in B16-F10 mouse melanoma cells. International Journal of Molecular Sciences, 26(11), 5063.
Wu, Y., et al. (2025). Nuclear partial segregation occurred in protoplast monokaryotization and asexual spore monosporous isolation of wild strains of Flammulina filiformis. Mycosystema.